Unravelling Immunosenescence from Single Cell and Spatial data

Nicolai Birkbak, Aarhus University
Grant amount: DKK 10,153,500

Nicolai Birkbak says: “The aim of this project is to unravel the mysteries of how our immune system changes as we age and how these changes influence our overall health. Using cutting-edge technology, we will delve into the intricacies of individual cells from thousands of people, with a particular focus on understanding how age and biological sex impact the immune system. Our goal is to develop innovative methods and apply advanced artificial intelligence tools to accurately measure the health and state of the immune system and demonstrate how immune health relates to general health and particularly to cancer development and outcome. This knowledge holds the potential to transform how we view the relevance of immune health. Potentially, it could pave the way for new immune-boosting strategies to prevent and treat various age-related diseases, offering a brighter and healthier future for individuals as they grow older.”

Project participants
Nicolai Birkbak
Associate Professor, Department of Clinical Medicine, Aarhus University